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Janknecht, Ralf

One or more keywords matched the following items that are connected to Janknecht, Ralf

Item Type	Name
Concept	Kelch-Like ECH-Associated Protein 1
Concept	Protein Domains
Concept	Glial Fibrillary Acidic Protein
Concept	Protein Biosynthesis
Concept	Cyclic AMP Response Element-Binding Protein
Concept	Protein Structure, Tertiary
Concept	Protein Isoforms
Concept	Protein Binding
Concept	Protein Conformation
Concept	Protein Kinases
Concept	Protein Processing, Post-Translational
Concept	Protein-Tyrosine Kinases
Concept	Protein Interaction Mapping
Concept	Ubiquitin-Protein Ligases
Concept	bcl-Associated Death Protein
Concept	Focal Adhesion Protein-Tyrosine Kinases
Concept	Bone Morphogenetic Protein 2
Concept	Bone Morphogenetic Protein 4
Concept	Protein Stability
Concept	RNA-Binding Protein EWS
Concept	Tumor Suppressor Protein p53
Concept	Protein Kinase Inhibitors
Concept	JNK Mitogen-Activated Protein Kinases
Concept	p38 Mitogen-Activated Protein Kinases
Concept	Mitogen-Activated Protein Kinase 3
Concept	Mitogen-Activated Protein Kinase 9
Concept	Ribosomal Protein S6 Kinases, 90-kDa
Concept	Cyclic AMP-Dependent Protein Kinases
Concept	Calcium-Calmodulin-Dependent Protein Kinases
Concept	BRCA1 Protein
Concept	Proto-Oncogene Protein c-ets-2
Concept	ets-Domain Protein Elk-1
Concept	ets-Domain Protein Elk-4
Concept	E1A-Associated p300 Protein
Concept	CREB-Binding Protein
Concept	Mitogen-Activated Protein Kinases
Concept	Mitogen-Activated Protein Kinase Kinases
Concept	Protein Subunits
Concept	Protein Transport
Concept	Protein Interaction Domains and Motifs
Concept	Proto-Oncogene Protein c-fli-1
Concept	Sex-Determining Region Y Protein
Concept	Smad1 Protein
Concept	Smad2 Protein
Concept	Smad3 Protein
Concept	Smad4 Protein
Concept	Smad7 Protein
Concept	Bone Morphogenetic Protein Receptors
Academic Article	Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1.
Academic Article	Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism.
Academic Article	Nuclear fusion of signaling pathways.
Academic Article	The versatile functions of the transcriptional coactivators p300 and CBP and their roles in disease.
Academic Article	Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300.
Academic Article	Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1).
Academic Article	Overexpression of the TGF-beta antagonist Smad7 in endometrial cancer.
Academic Article	Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D.
Academic Article	ETS transcription factor ERG cooperates with histone demethylase KDM4A.
Academic Article	Cooperation between ETS variant 2 and Jumonji domain-containing 2 histone demethylases.
Academic Article	Affinity purification of histidine-tagged proteins transiently produced in HeLa cells.
Academic Article	Signal integration at the c-fos promoter.
Academic Article	SAP1a is a nuclear target of signaling cascades involving ERKs.
Academic Article	Quantitative structure-activity analysis correlating Ras/Raf interaction in vitro to Raf activation in vivo.
Academic Article	Regulation of the c-fos promoter by the ternary complex factor Sap-1a and its coactivator CBP.
Academic Article	Interaction of the co-activator CBP with Myb proteins: effects on Myb-specific transactivation and on the cooperativity with NF-M.
Academic Article	Analysis of the ERK-stimulated ETS transcription factor ER81.
Academic Article	Role of focal adhesion kinase in MAP kinase activation by insulin-like growth factor-I or insulin.
Academic Article	The Ewing's sarcoma gene product functions as a transcriptional activator.
Academic Article	Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue.
Academic Article	Functional analysis of the transcription factor ER71 and its activation of the matrix metalloproteinase-1 promoter.
Academic Article	Regulation of Her2/neu promoter activity by the ETS transcription factor, ER81.
Academic Article	TGFbeta inducible early gene enhances TGFbeta/Smad-dependent transcriptional responses.
Academic Article	Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu.
Academic Article	Cloning of the murine ER71 gene (Etsrp71) and initial characterization of its promoter.
Academic Article	EWS-ETS oncoproteins: the linchpins of Ewing tumors.
Academic Article	Repression of transcription by TSGA/Jmjd1a, a novel interaction partner of the ETS protein ER71.
Academic Article	Concerted activation of the Mdm2 promoter by p72 RNA helicase and the coactivators p300 and P/CAF.
Academic Article	ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.
Academic Article	Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential.
Academic Article	Phosphorylated c-Jun and Fra-1 induce matrix metalloproteinase-1 and thereby regulate invasion activity of 143B osteosarcoma cells.
Academic Article	ETV1, 4 and 5: an oncogenic subfamily of ETS transcription factors.
Academic Article	Oncogenic features of the JMJD2A histone demethylase in breast cancer.
Academic Article	Elk-1 protein domains required for direct and SRF-assisted DNA-binding.
Academic Article	(HX)n repeats: a pH-controlled protein-protein interaction motif of eukaryotic transcription factors?
Academic Article	Heterogeneity of ternary complex factors in HeLa cell nuclear extracts.
Academic Article	Ras/Rap effector specificity determined by charge reversal.
Academic Article	Transcription. A growing coactivator network.
Academic Article	Signalling pathways: jack of all cascades.
Academic Article	Versatile molecular glue. Transcriptional control.
Academic Article	The ETS-related transcription factor ERM is a nuclear target of signaling cascades involving MAPK and PKA.
Academic Article	MAP kinase-dependent transcriptional coactivation by Elk-1 and its cofactor CBP.
Academic Article	The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136.
Academic Article	TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300.
Academic Article	CBP/p300 interact with and function as transcriptional coactivators of BRCA1.
Academic Article	Activation of Smad1-mediated transcription by p300/CBP.
Academic Article	Rapid and efficient purification of native histidine-tagged protein expressed by recombinant vaccinia virus.
Academic Article	Cell type-specific inhibition of the ETS transcription factor ER81 by mitogen-activated protein kinase-activated protein kinase 2.
Academic Article	HER2/Neu-mediated activation of the ETS transcription factor ER81 and its target gene MMP-1.
Academic Article	Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A.
Academic Article	Transcriptional regulation of Smad2 is required for enhancement of TGFbeta/Smad signaling by TGFbeta inducible early gene.
Academic Article	Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu.
Academic Article	HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81.
Academic Article	Vascular endothelial growth factor expression is up-regulated by EWS-ETS oncoproteins and Sp1 and may represent an independent predictor of survival in Ewing's sarcoma.
Academic Article	Succinate inhibition of alpha-ketoglutarate-dependent enzymes in a yeast model of paraganglioma.
Academic Article	Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase.
Academic Article	The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells.
Academic Article	Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D.
Academic Article	Distinct biochemical and functional properties of two Rab5 homologs from the rice blast fungus Magnaporthe oryzae.
Academic Article	Functional dissection of the transcription factor Elk-1.
Academic Article	JMJD5 links CRY1 function and proteasomal degradation.
Academic Article	Activation of ternary complex factor Elk-1 by MAP kinases.
Academic Article	Gene regulation by Ets proteins.
Academic Article	Activation of the Sap-1a transcription factor by the c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase.
Academic Article	Convergence of MAP kinase pathways on the ternary complex factor Sap-1a.
Academic Article	Phosphorylation of ETS transcription factor ER81 in a complex with its coactivators CREB-binding protein and p300.
Academic Article	Regulation of telomerase reverse transcriptase gene activity by upstream stimulatory factor.
Academic Article	Upregulation of the matrix metalloproteinase-1 gene by the Ewing's sarcoma associated EWS-ER81 and EWS-Fli-1 oncoproteins, c-Jun and p300.
Academic Article	Repression of Smad3 activity by histone demethylase SMCX/JARID1C.
Academic Article	Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81.
Academic Article	Histone demethylase JARID1B/KDM5B is a corepressor of TIEG1/KLF10.
Academic Article	Transcription factors ER71/ETV2 and SOX9 participate in a positive feedback loop in fetal and adult mouse testis.
Academic Article	Nephrin and Podocin functions are highly conserved between the zebrafish pronephros and mammalian metanephros.
Academic Article	A PGAM5-KEAP1-Nrf2 complex is required for stress-induced mitochondrial retrograde trafficking.
Academic Article	Clipping of arginine-methylated histone tails by JMJD5 and JMJD7.
Academic Article	The small members of the JMJD protein family: Enzymatic jewels or jinxes?
Academic Article	JMJD5 couples with CDK9 to release the paused RNA polymerase II.
Academic Article	Transcriptional activity and constitutive nuclear localization of the ETS protein Elf-1.
Academic Article	p38-2, a novel mitogen-activated protein kinase with distinct properties.
Grant	DYSREGULATION OF THE TRANSCRIPTION FACTOR ER81
Academic Article	Methylation of the epigenetic JMJD2D protein by SET7/9 promotes prostate tumorigenesis.

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Ataxia Telangiectasia Mutated Proteins